multicentric myxoid liposarcoma; a case report and literature review

Authors

mohammad gharehdaghi orthopedic research center, imam reza hospital mashhad university of medical sciences, mashhad, iran

mohammad hassani orthopedic research center, imam reza hospital mashhad university of medical sciences, mashhad, iran

ali r khooei department of pathology, imam reza hospital mashhad university of medical sciences, mashhad, iran

elaheh ghodsi orthopedic research center, imam reza hospital mashhad university of medical sciences, mashhad, iran

abstract

liposarcoma is a common malignant soft tissue tumor, accounting for 10% to 16% of all sarcomas. multicentric myxoid liposarcoma is an uncommon condition. differentiation between several primary tumors and metastasis of a single liposarcoma represents the main difficulty in diagnosis. a 47-years old woman presented with right thigh myxoid liposarcoma and underwent wide margin tumor resection. other investigations like cxr, abdominal and pelvic ct-scans were negative. after 18 months another myxoid liposarma was found in her ipsi-lateral breast without any evidence of other organs metastasis. second lesion location, time between two presentation and cytogenetic differences are accepted criteria to site a sarcoma in multicentric category, but in myxoid liposarcoma these can be explained by the special features inherent to this tumor.

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Journal title:
the archives of bone and joint surgery

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